Blood cancer treatment in India

IndiCure associated best cancer hospitals in India aim to provide highest quality and advanced oncology care in a compassionate environment. With great focus on the delivery of care and well being of patients, IndiCure associated best blood cancer hospitals in India offer latest therapies in state of the art infrastructure.

Overview

Blood cancer, also known as the haematological cancer is the cancer of the blood cells and the organs that form blood.

There are 3 major kinds of blood cancers:

  • Leukaemia
  • lymphoma
  • Multiple myeloma.

All these cancers develop either in the bone marrow or the lymphatic tissue in the body and affect the blood cell production and the immune response from the disease to great extent.

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Leukaemia is the cancer of white blood cell that starts in bone marrow, which is the production house of the blood cells including WBCs that protect us from infections, RBCs that carry and provide oxygen to all the parts of our body and platelets that help to clot the blood during injury. In leukaemia, the bone marrow produces plenty of abnormal white blood cells which do not work normally and they tend to grow faster and invade other normal blood cells leading to problems like bleeding, anaemia and infections. It can advance and spread to the lymph nodes or other organs and produce the symptoms.

Leukaemia can be acute or chronic. It can affect only WBCs or can affect other cells that usually develop into RBC, granulocytes or platelets (Myelogenous leukaemia). So in general there are 4 main types of leukaemia;

  • Acute lymphoblastic leukaemia (ALL)
  • Acute Myelogenous leukaemia(AML)
  • Chronic lymphocytic leukaemia(CLL)
  • Chronic Myelogenous leukaemia(CML)
Causes

It is difficult to pin point the exact cause, but doctors say that the following are strongly suspected causes that may result in developing blood cancer;

  • Exposure to artificial ionizing radiation
  • Infection by viruses like HTLV-1 (human T-lymohotropic virus) and HIV
  • Maternal foetal transmission which is rare
  • Genetic predisposition
  • Down syndrome.
Treatment options

There are various treatment options for Blood cancer. The treating doctor would suggest the best treatment for the patient or a combination of these depending upon the medical condition of the patient:

  1. Chemotherapy: This is considered as the main treatment for blood cancer.
  2. Radiation therapy: This is done to shrink the tumour mass which is compressing the important structure of the body. This is mainly employed in cases of localized disease.
  3. Biological therapy: In this, body uses its own immune system to destroy cancer cell. Biological agents like interferon, interleukins, tumour necrosis factors, monoclonal antibodies and colony stimulating factors are used as special immune system cells to stimulate the body's immune system so as to destroy and kill the cancerous cells.
  4. Bone marrow transplants: also known as the stem cell transplant is most frequently performed procedure for the treatment of leukaemia and lymphomas. In this the damaged bone marrow is replaced with the new and healthy one from either a donor or from your body. Bone marrow transplant can be performed in 3 ways
    • Autologous BMT: During Autologous bone marrow transplant, stem cells are removed from your body before undergoing the chemotherapy or radiation therapy and are preserved. After the chemo/radiation they are put back in the body to produce normal blood cells.
    • Allogenic BMT: During Allogenic Bone marrow transplant, stem cells are taken from the donor whose genes are partly matching yours like your brother or sister can be the best match for you.
    • Umbilical cord blood transplant: During umbilical cord blood transplant, stem cells are taken from the umbilical cord (which were preserved when the patient was born) and there is no need for matching.
Candidates

Bone Marrow Transplant is a complex and major procedure. There are risks and complications associated with the procedure and the procedure is thus recommended to select few patients when other treatments have failed.

Bone Marrow Transplant is recommended if other treatments are not working and there is higher risk of the condition returning without the transplant. If the physician feels that the benefits of the transplant outweigh the risks associated with the procedure, bone marrow transplant is advised. The best candidates for bone marrow transplant are those in otherwise good health and have stem cells available from a sibling, or another family member, with the same tissue type.

Procedure

Bone Marrow Transplant or Stem cell transplant is a complex procedure done in several stages.
  1. Physical examination to find if the patient is in a state to accept the Bone Marrow Transplant. Several tests are performed on the vital organs like lungs, kidneys, heart, and liver to make sure that the patient can accept the transplant.
  2. Stem cell harvesting from the donor- The process of harvesting the bone marrow cells remains the same regardless of the type of transplant- allogenic or autologous. This is done under general anaesthesia. At first, the needle is inserted into the cavity of the backside of hip bone or iliac crest and bone marrow is collected. This is the place where large quantity of bone marrow is present. The bone marrow is purged to remove any cancerous cells in case of autologous transplant or removed for T cells to prevent rejection in case of allogenic transplant and frozen at a temperature between ---80 to -196 degrees.
  3. Preparing the patient's body for transplant- this includes chemotherapy and/or radiation to kill cancerous cells and make place for the new bone marrow.
  4. Bone Marrow Transplantation- this is done 1-2 days after the last session of chemotherapy/ radiation therapy. During transplantation, the stem cells harvested are infused intravenously the same way as any blood product is given. A frequent check is kept on the patient for any signs of fever, chills, hives or chest pain. As the transplant is completed, the days of waiting begin.
  5. Check for complications or rejection- Two to four weeks after bone marrow transplant are most critical since high doses of chemotherapy/ radiotherapy have destroyed the patient's bone marrow, crippling body's immune system. Before the new marrow migrates to cavities of the large bones and begin to produce normal cells, the patient is quite susceptible to infection and excessive bleeding. Multiple antibiotics, blood transfusions, platelet transfusions are administered to the patient. In case of allogenic transplant, additional medications to prevent rejection are also given. Extraordinary precautions are taken to prevent infection. The patient is constantly monitored to check if engraftment has occurred or not and to monitor organ function. Once the healthy bone marrow begins to produce normal cells, transfusion is stopped.
Recovery

Recovery after Bone Marrow Transplant is long and stressful, both physically and emotionally for the patient and family as well. First 100 days are critical, when there are high chances of complication or rejection of the transplant. Patient is carefully monitored during this span. Patient feels fatigued, weak and is unable to concentrate for first few weeks after the transplant. Full recovery may take up to a year or two.

Expected Results

Treatment outcomes after Bone Marrow Transplant have improved in years. It is a lifesaving procedure and a successful transplant helps save the life of a person which was otherwise not possible

Time

You would need a total of 16-18 weeks in India for a Bone Marrow transplant operation and recovery before you can go back to your country.

Best Hospital for Blood cancer in India a

At IndiCure we recognize the significance of excellent health and well-being of our guests and hence our objective is to provide best leukaemia treatment in India at honest affordable prices. A preferred association with best blood cancer hospital in Indiaand top oncology surgeons in India helps us advice

  • Best leukaemia treatment in India
  • Best hospital for blood cancer treatment in India

The cost of blood cancer treatment in India varies with the type of procedure chosen, patient's medical condition, facility and city where you choose to get the surgery done.

An individually allocated case manager takes personalized interest to design a tailor made treatment plan for every guest and will provide with details about the best blood cancer hospital in India.

Medical history and diagnostic reports may be sent to info@indicure.com for an early response from the case managers.

IndiCure Cares

We encourage you to educate yourself about blood cancer treatment in India, benefits from the right kind of procedure and then make an informed decision.

IndiCure thus invites you for a free consultation with chosen best blood cancer hospital in India and top oncologists in India and assures you hassle free arrangements for examinations, procedures, recovery, travel and stay in India.

You can be rest assured that with IndiCure's expertise, we bring in a wonderful experience of medical tourism in India, which we have been doing so for almost a decade now.