Multiple Sclerosis treatment in India

It is a well known fact that there is no known cure for Multiple sclerosis. The goal of the treatment is to limit the MS attacks and prevent further disability. There have been various studies going on around the world about the effect of CCSVI liberation on Multiple Sclerosis. Few hospitals in India have been treating patients of MS with CCSVI liberation and the findings at these best hospitals in India and CCSVI clinics in India are as follows:

  • 60% show subjective improvement
  • 40% show objective improvement
  • More improvement last 50 cases - learning curve
  • Commonly improvements are seen as:
    • Better balance - and walking
    • Strength in lower limbs
    • Feeling of warmth
    • Disappearance of mental fogging
    • Swallowing
    • Bladder incontinence
    • Vision

According to the research, The Liberation procedure does improve symptoms in many patients and some of the improvements may come slowly.

Overview

Multiple sclerosis is the chronic inflammatory demyelinating disease of central nervous system. It is an autoimmune disorder and is characterised by the production of antibodies that damage the nerve myelin sheath and ultimately the nerve itself. This leads to production of the significant physical disability commonly called as paralysis along with other symptoms like paraesthesia, intention tremor, scanning speech, nystagmus, heat intolerance, bowel and bladder dysfunction, sharp pain, ataxia, tremors and many more.

It has been found that clinical condition named as CCSVI, that is chronic cerebrospinal venous insufficiency is one of the factors that add to the damage of nerves or nervous system in multiple sclerosis.

MULTIPLE SCLEROSIS affects largely the young adults between the age of 20-40 years and is more common in women.

It is an autoimmune disease which is induced by viral and several other infectious agent which leads to increased antibodies in the cerebrospinal fluid that elicits the autoimmune response resulting in nerve damage.

Categories of Multiple Sclerosis

Depending on the progression and relapses of the MULTIPLE SCLEROSIS, it has been sub divided into four types;

  • Relapsing remitting MULTIPLE SCLEROSIS: most common which is characterised by relapses that is the acute worsening of the neurological functioning and remission which is the span without progression of disease along with partial or complete abatement of symptoMultiple Sclerosis.
  • Secondary progressive MULTIPLE SCLEROSIS: most of the patients with RRMULTIPLE SCLEROSIS usually develops SPMULTIPLE SCLEROSIS which begins with the relapsing and remitting course followed by the progression of the symptoMultiple Sclerosis.
  • Progressive relapsing MULTIPLE SCLEROSIS: It is progressive disease from the onset which is marked by continue disease progression between the relapses. It is seen mostly in people with MULTIPLE SCLEROSIS after 40 years of age.
  • Primary progressive MULTIPLE SCLEROSIS: It is the rare form characterized by continuous worsening of the disease from the onset without plateaus or temporary improvements.
Causes

The precise cause of MULTIPLE SCLEROSIS is unknown. However, the following factors play a vital role in progression of the MULTIPLE SCLEROSIS.

  1. Immunological
    Multiple Sclerosis is autoimmune disease which is believed to be induced by viral or infectious agents leading to breakdown of the immune system that ultimately destroys nervous system.
  2. Genetic
    Genetic susceptibility plays an important role in development of Multiple Scleros. It has been proved that if one of the parents has MS, then their children are at high risk of getting the disease.
  3. Infection
    Bacterial or viral infection can trigger Multiple Sclerosis as they are responsible and known to cause demyelination. These viruses includes herpes virus 6, chlamydial pneumonia, Epstein-Barr etc.
Treatment options

There is no known cure for Multiple Sclerosis. The focus of the treatment is to limit MS attacks and prevent further disability.

  1. Drug therapy: There are certain drugs which can modify the course of M S or can reduce the symptoms.
    Drugs to modify the MULTIPLE SCLEROSIS:
    Beta interferon and glatiramer is the drug of choice prescribed to reduce the relapses of MS
    Drugs to suppress immunity:
    Drugs like azathioprine, methotrexate and cyclophosphamide are given as they decrease the immunity thereby reducing the risk of further nerve and nerve sheath damage.
    Drugs to manage the symptoms:
    • Corticosteroids- like prednisone to reduce inflammation and to treat the relapses for decreasing the duration of each episode
    • Muscle relaxants- like baclofen, tizanidine to reduce the muscle spasticity.
    • Anticholinergics- to help control the bowel and bladder dysfunctions
    • Antiviral and Dopamine Agonist- to reduce fatigue
    • Gabapentin, carbamazepine, phenytoin to lessen pain
    • Antidepressants- to control depression associated with MULTIPLE SCLEROSIS
  2. Physical therapy and Occupational Therapy: This should be encouraged in patients with multiple sclerosis to improve their quality of life and to make their daily life easier and productive.
  3. Surgical options:
    • Deep brain stimulation:
      Usually it is performed to control tremors and is only considered when other options have failed. During the procedure a device is implanted in the brain which helps to improve the symptoms by blocking the nerve signals that cause severe and disabling tremors.
    • Drug catheter/pump implantation:
      This is performed to reduce pain and spasticity. A catheter or a pump is implanted in the lower portion of the spine to provide constant flow of medicine preferably baclofen.
    • CCSVI Liberation
      CCSVI stands for chronic cerebrospinal venous insufficiency. Chronic cerebrospinal venous insufficiency is the narrowing of veins which carry blood away from the brain and spinal cord. The basic premise is that when blood flow is slowed, the blood backs up into the brain and spinal cord leading to oxygen loss and iron deposits in the brain.
      In 2009, Italian researcher Paolo Zamboni, MD, introduced the idea that CCSVI might cause MS or make the symptoms worse. He used ultrasound to compare the blood flow in people with and without MS and found abnormal blood flow in 100% people with MS.
      CCSVI liberation or opening up blocked vessels can improve MS or no is still a matter of debate. Some researchers state that there has definitely improvement in symptoms of patients who undergo liberation treatment while some do not believe it. It is an endovascular procedure which involves placing a stent or balloon inside the blocked vein to open it and restore the blood flow.
Candidates

If you have been suffering from above mentioned symptoms, and if the reports of your laboratory test are indicating the signs of breast cancer and you are diagnosed with the breast cancer then you should undergo the treatment at the earliest.

Procedure

Deep brain stimulation:

The procedure is done under general anaesthesia. The surgeon locates the area to be treated either by using the MRI / CT scan or using the electrode recording technique for mapping and targeting the brain area to be treated. After locating the area, the electrodes are implanted in the target area whose loose end in placed under the skin of the head and the incisions are sutured back.

The second part of the surgery is the placement of the impulse generator in the chest. It is done using general anaesthesia and generator is placed and positioned to connect with the electrode using extension wires.

Baclofen pump implantation

The surgery is performed under general anaesthesia. The surgeon will first place the pump just beneath the skin of your abdomen which is connected to the catheter that is thin and flexible silicon tube. In the second part of the surgery, the catheter is threaded under skin inside intrathecal space surrounding the spinal cord. At this place there will be constant delivery of the medicine to relieve spasticity.

CCSVI liberation

CCSVI liberation is an endovascular procedure and done by a team of neurologist, neurovascular interventional radiologist in a state of the neuroendovascular lab with built in CT. Procedure is performed in local anesthesia along with sedation. Venography is performed through one of the leg veins followed by balloon angioplasty of stenosis. Re-evaluation is done after the procedure through Doppler, neurology to study the response of the procedure.

Recovery

Recovery following the procedures is simple and quick. The patient would need to stay at the hospital for a day or two and another week to ten days in India before he/ she can go back.

Expected Results

Deep brain stimulation offers a definite treatment for the control tremors of the arm. DBS may help the tremors of the head and body, but the treatment is aimed at treating arm tremors. DBS is not known to help other symptoms of MS.

CCSVI liberation is still in research phase and long term results of the treatment are still unknown, though research has shown liberation to help and improve symptoms in many patients.

Time

Time required in India for the treatment of multiple sclerosis depends on the patient's medical condition and what treatment plan you are looking at. Your case manager would guide you about the time required for multiple sclerosis treatment in India.

CCSVI clinic in India

At IndiCure we recognize the significance of excellent health and well-being of our guests and hence our objective is to provide best MULTIPLE SCLEROSIS treatment in India at honest affordable prices. A preferred association with best CCSVI clinics in India and top neuro surgeons in India helps us advise

  • The best multiple sclerosis treatment in India
  • The most affordable cost of multiple sclerosis treatment in India

The cost of multiple sclerosis treatment in India varies with the type of procedure chosen, patient's condition, facility and the city where you choose to get the treatment done.

An individually allocated case manager takes personalized interest to design a tailor made treatment plan for every guest and will provide with a specific time and cost of multiple sclerosis treatment in India.

Medical history and diagnostic reports may be sent to info@indicure.com for an early response from the case managers.

IndiCure Cares

We encourage you to educate yourself about multiple sclerosis treatment in India, benefits from the right kind of procedure and then make an informed decision.

IndiCure thus invites you for a free consultation with chosen best neurosurgery hospitals in India and top neurosurgeons in India and assures you hassle free consultation for examinations, procedures, recovery, travel and stay in India.

You can be rest assured that with IndiCure's expertise, we bring in a wonderful experience of medical tourism in India, which we have been doing so for almost a decade now.