Bone marrow transplant in India
We at IndiCure understand that Bone marrow transplant is a serious treatment. And thus, associate only with the best doctors and hospitals in India which have the most advanced infrastructure to deliver the highest quality and best outcomes for bone marrow treatment. The patient is treated with great compassion and care and we make sure that you get the best services for your bone marrow transplant in India. Besides, the cost of bone marrow transplant in India is much less and affordable as compared to Western countries.
Bone marrow is an essential spongy, fatty tissue substance present inside the bones of human body. It produces the blood forming cells in the human body that includes;
Red blood cells that carries oxygen and essential nutrients throughout the body
White blood cells that protects our body from any infections
Platelets for blood clot formation to prevent the excessive blood loss during injury.
Apart from these cells, the bone marrow also contains hematopoietic stem cell (HSC) which are unspecialized and immature stem cells having the ability to divide and become either the stem cell or differentiate and mature into other different kinds of blood cells.
Bone marrow cells starts to malfunction as a result of disease like leukaemia, aplastic anaemia, cancers or other immune deficiency disorder and starts yielding defective or abnormal blood cells that affect the normal functioning of the human body.
Bone marrow transplant is required when the bone marrow in human body is not healthy enough to perform its normal function which can be due to any disease, chronic infections or aggressive cancer treatments. Some of the common reasons to undergo bone marrow transplant include;
- Cancers like leukaemia, lymphoma and multiple myeloma that affect the bone marrow cells.
- Aplastic anaemia in which the bone marrow stops producing new blood cells.
- Inherited blood disorders like sickle cell anaemia and thalassemia
- Congenital neutropenia resulting in recurrent infections
- Damage to bone marrow due to aggressive chemotherapy etc.
Bone Marrow Transplant is a major and complex procedure and requires thorough and meticulous planning and forethought.
Bone marrow transplant is of two types;
- Allogenic bone marrow transplant: When the donor is some other person whose tissue has the same genetic type as the patient, the bone marrow transplant is termed as allogenic transplant. The donor is most likely to be a brother or sister of the patient. However, it is only in 35% of the cases that sibling's marrow is a perfect match.
- Autologous bone marrow transplant: When healthy stem cells are taken from the patient's own body and replaced with diseased blood cells, the procedure is termed as autologous bone marrow transplant.
Bone Marrow Transplant is a complex and major procedure. There are risks and complications associated with the procedure and the procedure is thus recommended to select few patients when other treatments have failed.
Bone Marrow Transplant is recommended if other treatments are not working and there is higher risk of the condition returning without the transplant, and if the physician feels that the benefits of the transplant outweigh the risks associated with the procedure. The best candidates for bone marrow transplant are those in otherwise good health and have stem cells available from a sibling, or another family member.
The procedure needs meticulous planning and the surgeon thoroughly assesses the patient to make sure that he/she is healthy enough to survive and accept the transplant. For this, series of tests are done to assess patient's vital organs like heart, lungs, kidneys, liver to ensure the patient is physically capable to accept the transplant.
If the surgeon thinks that transplant can be done, he proceeds with harvesting of stem cells.Harvesting stem cells:
If the patient is undergoing allogenic transplant, bone marrow is harvested from the donor one or two days prior to the transplant procedure. The stem cells are collected in two ways;
- Bone marrow harvesting: The donor is given general anaesthesia and the cells are collected using a needle from rear part of the hip bone or the iliac crest where the stem cells are located in abundance.
- Leukapheresis: This is done in cases of autologous transplant in which the blood is drawn intravenously from the patient's body and the machine is used that separates the white blood cells containing stem cells from the blood.
Before the transplant, the patient undergoes chemotherapy or radiation therapy to kill the cancerous cells and to make room for the new bone marrow cells often known as conditioning of the patient.Stem cell transplant:
For transplant, the central venous catheter or a port is installed on the upper right portion of the chest wall of the patient and the new stem cells are infused through this port that help them to flow directly to your heart from where they are dispersed all over the body through the blood. Gradually the cells become established in the bone marrow to grow.Engraftment:
The post is kept at same place as the infusion is done in multiple sessions that aid the new stem cells to integrate in the body. This process is known as engraftment. The patient receives the blood transfusion, fluids, antibiotics, platelet transfusion through this port so as to fight the infection and to help your body accept the new marrow.Monitoring for complications:
After the infusion, you will be closely monitored for any signs of complications or rejection. Precautions are taken to prevent any infections. The patient is constantly monitored to check if engraftment has occurred or not and to monitor organ function. Once the healthy bone marrow begins to produce normal cells, transfusion is stopped.
It is a complex but lifesaving procedure which has improved in past few years. After a successful bone marrow transplant, you will be able to live normal life once again which was not possible otherwise.
Recovery after bone marrow transplant is long and stressful process for both the patient and the family. Initial few weeks are very critical as there are high chances of complications and rejections of the transplant.
But, subsequently the patient starts to feel better as the blood count begins to grow and his immune system becomes stronger. Full recovery may take up to an year or two.
Time and Cost
You shall need a total of 16-18 weeks for bone marrow transplant in India after which you can fly back to your country.
Cost of Bone Marrow transplant in India
At IndiCure, we recognize the significance of excellent health and well-being of our guests and hence our objective is to provide best bone marrow transplantation in India at honest affordable prices. A preferred association with best hospitals for bone marrow transplant in India and top surgeons for bone marrow transplant in India helps us advise:
- Best stem cell transplant in India
- Most affordable cost of bone marrow transplant in India
The cost of bone marrow transplant in India varies with the medical condition of the patient, type of procedure, facility and the place of the treatment.
The cost of bone marrow transplant in India starts from around USD 20,000 and varies with various factors
An individually allocated case manager takes personalized interest to design a tailor made treatment plan for every guest and will provide with a specific time and bone marrow transplantation cost in India
Medical history and diagnostic reports may be sent to email@example.com for an early response from the case managers.
We encourage you to educate yourself about bone marrow transplantation in India, benefits from the right kind of procedure and then make an informed decision.
IndiCure thus invites you for a free consultation with chosen best hospitals for bone marrow transplant in India and top surgeons in India and assures you hassle free arrangements for examinations, procedures, recovery, travel and stay in India.
You can be rest assured that with IndiCure's expertise, we bring in a wonderful experience of medical tourism in India, which we have been doing so for almost a decade now.